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TS-IS -  TS-IS is a medical reference, web community and research organisation.
CRONE Portal -  Crone is an informational list about proper uses of female hormones. This list is designed for, and membership is limited to, persons who are undergoing, or will undergo, a course of female hormone replacement therapy. This is a high-bandwidth list where the moderators keep the discussion strictly on-topic.
TG Links -  An excellent site with lots of information on it for transgendered people, although it doesn't appear to have been updated for some time.
Endocrinology - An Integrated Approach -  by Stephen Nussey and Saffron Whitehead.
An online textbook on endocrinology.
The International Journal of Transgenderism -  This electronic journal is a vehicle for the transmission of scholarly work in the area of transgenderism (gender identity). It contains many articles and is an important source of information and exchange of ideas around the subject of gender identity.
Press For Change -  Press for Change is a political lobbying and educational organisation, which campaigns to achieve equal civil rights and liberties for all transgender people in the United Kingdom, through legislation and social change.
WWW.TRANSSEXUAL.ORG.UK -  Transsexual UK is a web portal and e-zine providing links for transsexual people and their allies to relevant groups, organisations and resources in the United Kingdom.

Transsexual UK
- a good support and social email Yahoo group for transsexuals who feel lonely and isolated. There are lots of resources on legal and medical matters.
Mermaids - is a support group for gender variant children and teenagers. Their Aims are simple: They aim to support children and teenagers up to the age of 19, who are trying to cope with gender identity issues.

Depend - are a voluntary organisation whose aim is to provide support, advice and information for anyone who knows, or is related to, a transsexual person in the UK.